Skip to main content

Does the Dog Represent an Animal Model of Asthma?

Buy Article:

$39.50 plus tax (Refund Policy)

Abstract:

Rather than representing a true animal model of asthma, the dog provides a spectrum of airway responsiveness. The most reactive dogs resemble asthmatics in that they demonstrate non-specific bronchial hyper-reactivity. Varying degrees of vagal contribution do not account for the spectrum. Although variations in H2 receptor stimulation and varying degrees of sympatho-adrenal modulation account for some of the spectrum with respect to histamine, these factors do not affect responses to other agents such as methacholine. With regard to allergy, if a narrow spectrum of airway responsiveness is examined, there is a good correlation between skin and airway reactivity to antigen.

Document Type: Research Article

DOI: http://dx.doi.org/10.2500/108854181779091317

Publication date: September 1, 1981

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Information for Advertisers
  • Reprint Requests
  • www.AJRA.com
  • www.AllergyandRhinology.com
  • Ingenta Connect is not responsible for the content or availability of external websites
ocean/aap/1981/00000002/00000004/art00008
dcterms_title,dcterms_description,pub_keyword
6
5
20
40
5

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more