Stem cells: The therapeutic role in the treatment of diabetes mellitus
Authors: Adams, Gary G.; Buttery, Lee; Stolnik, Snow; Morris, Gordon; Harding, Stephen; Wang, Nan
Source: Biotechnology and Genetic Engineering Reviews, Volume 27, Number 1, November 2010 , pp. 285-303(19)
Publisher: Nottingham University Press
Abstract:
The unlimited proliferative ability and plasticity to generate other cell types ensures that stem cells represent a dynamic system apposite for the identification of new molecular targets and the production and development of novel drugs. These cell lines derived from embryos could be used as a model for the study of basic and applied aspects in medical therapeutics, environmental mutagenesis and disease management. As a consequence, these can be tested for safety or to predict or anticipate potential toxicity in humans. human Es cell lines may, therefore, prove clinically relevant to the development of safer and more effective drugs for patients presenting with diabetes mellitus.Document Type: Research article
Publication date: 2010-11-01
- The hugely important areas of Biotechnology and Genetic Engineering underpin the production of drug delivery systems, the making of healthier food products, the design of health-care products, the making of antisera and vaccines - and even the efficient extraction of oil from the harsh environment of a deep well: these are among the Biotechnology processes which depend in fundamental terms on our ability to handle giant molecular complexes of living origin. Furthermore, molecular biologists and chemists are now increasingly able to 'engineer' new types of proteins and complexes, over and beyond those which 3 billion years of evolution have provided. These advances have been covered by a plethora of literature and journals, to such an extent it is often difficult for a Researcher or an Industrialist to keep informed of the advances in the state of the art. Biotechnology and Genetic Engineering Reviews is a long established annual volume designed to address just this. Invited contributions from top experts in their respective fields in both academia and Industry provide detailed and comprehensible reviews helping researchers keep pace with the laltest advances.
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