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Hendrik Peter Bernelot Moens (1931-2008)

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The synaptonemal complex (SC) is a proteinaceous structure that physically holds the two homologous chromosomes together during meiotic prophase. First observed in 1956 by Montrose J. Moses (Duke University, Durham, North Carolina) in meiotic prophase spermatocytes of crayfish, the SC was found in many other species. Initially, the research into the SC focused on its structural characteristics, but with the availability of antibodies, the focus shifted to the protein components of the complex, and later, attention was diverted to the proteins associated with this structure at different time points during meiotic prophase. Various possible roles of this meiotic-specific structure have been debated since the discovery of the SC structure but consensus has yet to be reached. Dr. Peter Moens has been an internationally recognized expert on the SC, being involved in all of the steps and characterizing many of the structural and functional components of the complex mainly in mice but also in other species.

Le complexe synaptonémique (SC) est une structure protéique qui lie physiquement les deux chromosomes homologues ensemble lors de la prophase méiotique. D’abord observée en 1956 par Montrose J. Moses (Université Duke, Durham, Caroline du nord) en prophase méiotique chez les spermatocytes de l’écrevisse, le SC a été observé chez de nombreuses autres espèces. Initialement, la recherche sur le SC a porté sur ses caractéristiques structurales. Ensuite, avec la disponibilité d’anticorps, l’attention s’est concentrée sur les protéines du complexe pour ensuite focaliser sur les protéines associées à cette structure tout au long du déroulement de la prophase méiotique. Divers rôles possibles pour cette structure spécifique de la méiose ont fait l’objet de débats depuis la découverte du SC, mais aucun consensus à cet égard n’a été atteint. Le Dr Hendrik Peter Bernelot Moens était un expert reconnu internationalement pour ces travaux sur le SC; il a été actif à toutes les étapes et a contribué à caractériser plusieurs des composantes structurales et fonctionnelles du complexe, principalement chez la souris mais également chez d’autres espèces.

Document Type: Research Article

Publication date: 2008-12-01

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  • From its inception in 1957, this international cytogenetics journal has catered to the research areas of the members of the Genetics Society of Canada; traditionally, these have included agriculture, entomology, genetics/cytogenetics, and evolutionary mechanisms. The contents of the journal have evolved as contributors developed new technologies and interests. A 20-member Editorial Board is composed of scientists from around the world. Reviews and commentary from respected experts are often featured.
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