Gene amelioration demonstrated: the journey of nascent genes in bacteria

Authors: Golding, G. B.; Marri, Pradeep R.e.d.d.y.

Source: Genome, Volume 51, Number 2, February 2008 , pp. 164-168(5)

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Abstract:

Gene amelioration is the hypothesis that genes acquired via lateral gene transfer will, over time, acquire the molecular characteristics of the host genome. Species for which multiple strains have been sequenced permit a demonstration that this hypothesis is correct. We use 7 sequenced genomes of Streptococcus pyogenes and 6 sequenced genomes of Staphylococcus aureus to illustrate the action of amelioration on these genomes.

L'amélioration génique est une hypothèse selon laquelle des gènes acquis via transfert latéral en viendront, au fil du temps, à acquérir les caractéristiques moléculaires de leur génome-hôte. Des espèces chez lesquelles plusieurs souches ont été séquencées permettent d'en faire la démonstration. Les auteurs ont employé sept génomes séquencés du Streptococcus pyogenes et six génomes séquencés du Staphylococcus aureus pour illustrer l'impact de l'amélioration sur ces génomes.

Document Type: Research article

Publication date: 2008-02-01

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From its inception in 1957, this international cytogenetics journal has catered to the research areas of the members of the Genetics Society of Canada; traditionally, these have included agriculture, entomology, genetics/cytogenetics, and evolutionary mechanisms. The contents of the journal have evolved as contributors developed new technologies and interests. A 20-member Editorial Board is composed of scientists from around the world. Reviews and commentary from respected experts are often featured.
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