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Effects of different doses of medetomidine and tiletamine–zolazepam on the duration of induction and immobilization in free-ranging yearling brown bears (Ursus arctos)

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We compared anesthetic protocols with different doses of tiletamine–zolazepam (TZ) combined with medetomidine (M) for 288 yearling brown bear (Ursus arctos L., 1758) immobilizations with the objective of finding a combination of doses that would provide fast induction with a duration of anesthesia long enough to minimize the need for administering additional drug. The duration of induction time and immobilization was dose-dependent. Increasing the M dose resulted in significantly shorter induction times and a lower probability of giving supplemental drugs. Increasing the TZ dose prolonged duration of anesthesia. For yearling brown bears in Scandinavia, captured shortly after den emergence in April and May, we recommend total dart doses of 1.0–1.66 mg M/dart, plus 62.5–125 mg TZ/dart, depending on the individual requirements for the length and depth of anaesthesia.

Keywords: Ursus arctos; brown bear; grizzli; immobilisation; immobilization; induction time; medetomidine; médétomidine; ours d’un an; période d’induction; tiletamine; tilétamine; yearling; zolazepam; zolazépam

Document Type: Research Article


Affiliations: 1: Leibniz-Institute for Zoo and Wildlife Research, Alfred-Kowalke Straße 17, 10315 Berlin, Germany. 2: Faculty of Arts and Sciences, Department of Environmental and Health Studies, Telemark University College, N-3800 Bø i Telemark, Norway. 3: Department of Forestry and Wildlife Management, Hedmark University College, Campus Evenstad, NO-2418, Elverum, Norway. 4: Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, P.O. Box 7054, SE-750 07 Uppsala, Sweden. 5: Scandinavian Brown Bear Project, Noppikoski 156, SE-79498 Orsa, Sweden. 6: Department of Ecology and Natural Resource Management, Norwegian University of Life Sciences, Post Box 5003, NO-1432 Ås, Norway.

Publication date: June 10, 2012

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  • Published since 1929, this monthly journal reports on primary research contributed by respected international scientists in the broad field of zoology, including behaviour, biochemistry and physiology, developmental biology, ecology, genetics, morphology and ultrastructure, parasitology and pathology, and systematics and evolution. It also invites experts to submit review articles on topics of current interest.
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