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Stem cells and regenerative medicine — future perspectives

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Abstract:

Stem cell research has expanded at an exponential rate, but its therapeutic applications have progressed much more slowly. Currently, the research focuses on understanding embryonic, adult, and inducible pluripotent stem cells. Translation of adult stem cell research has established a definitive benefit that is greater than that of the current standard of care in the field of cardiovascular medicine. The future of stem cell research and therapy will continue to provide novel avenues of diagnostics, therapeutics, and tissue regeneration. Here we discuss a brief history of stem cell research as it transitioned from the 20th to the 21st century. We address lessons learned in the first decade of the new millennium that could help guide others to translate research into therapy across disciplines. Finally, we highlight future goals and challenges that must be overcome and offer some perspective on the bright future of stem cell research and therapy.

Keywords: avenir; cellules souches; clinical; clinique; future; histoire; history; médecine régénératrice; regenerative medicine; stem cells

Document Type: Research Article

DOI: https://doi.org/10.1139/y2012-007

Affiliations: Division of Cardiovascular Surgery and Toronto General Research Institute, MaRS Centre, Toronto Medical Discovery Tower, 101 College Street, University Health Network, Toronto, ON M5G 1L7, Canada.

Publication date: 2012-03-16

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  • Published since 1929, this monthly journal reports current research in all aspects of physiology, nutrition, pharmacology, and toxicology, contributed by recognized experts and scientists. It publishes symposium reviews and award lectures and occasionally dedicates entire issues or portions of issues to subjects of special interest to its international readership.
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