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Published since 1929, this monthly journal reports current research in all aspects of physiology, nutrition, pharmacology, and toxicology, contributed by recognized experts and scientists. It publishes symposium reviews and award lectures and occasionally dedicates entire issues or portions of issues to subjects of special interest to its international readership.

Publisher: NRC Research Press

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Volume 86, Number 8, August 2008

The endothelin axis in cancer: the promise and the challenges of molecularly targeted therapy
pp. 473-484(12)
Authors: Spinella, Francesca; Rosanò, Laura; Bagnato, Anna

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Endothelin: 20 years from discovery to therapy
pp. 485-498(14)
Authors: Barton, Matthias; Yanagisawa, Masashi

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Endothelin receptor B-mediated induction of c-jun and AP-1 in response to shear stress in human endothelial cells
pp. 499-504(6)
Authors: Morawietz, H.; Wagner, A.H.; Hecker, M.; Goettsch, W.

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Polymorphisms of EDNRB, ATG, and ACE genes in salt-sensitive hypertension
pp. 505-510(6)
Authors: Caprioli, Jessica; Mele, Caterina; Mossali, Chiara; Gallizioli, Laura; Giacchetti, Gilberta; Noris, Marina; Remuzzi, Giuseppe; Benigni, Ariela

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Inhalation of an endothelin receptor A antagonist attenuates pulmonary inflammation in experimental acute lung injury
pp. 511-515(5)
Authors: Kalk, Philipp; Senf, Philine; Deja, Maria; Petersen, Bodil; Busch, Thilo; Bauer, Christian; Boemke, Willehad; Kaisers, Udo; Hocher, Berthold

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Distinct modulation of the endothelin-1 pathway in iNOS−/− and eNOS−/− mice
pp. 516-525(10)
Authors: Labonté, Julie; Brochu, Isabelle; Simard, Elie; D’Orléans-Juste, Pedro

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Antagonism of endothelin-1 inhibits hypoxia-induced apoptosis in cardiomyocytes
pp. 536-540(5)
Authors: Ren, Anjing; Yan, Xiaohong; Lu, Hong; Shi, Jingsong; Yin, Yuanjun; Bai, Jie; Yuan, Wenjun; Lin, Li

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Pulmonary fibrosis in l-NAME-treated mice is dependent on an activated endothelin system
pp. 541-545(5)
Authors: Mach, Alexander; Thone-Reineke, Christa; Godes, Michael; Heiden, Susi; Sharkovska, Yuliya; von Websky, Karoline; Relle, Katharina; Hocher, Berthold; Kalk, Philipp

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Nonpeptidic antagonists of ETA and ETB receptors reverse the ET-1-induced sustained increase of cytosolic and nuclear calcium in human aortic vascular smooth muscle cells
pp. 546-556(11)
Authors: Bkaily, Ghassan; Choufani, Sanaa; Avedanian, Levon; Ahmarani, Lena; Nader, Moni; Jacques, Danielle; D’Orléans-Juste, Pedro; Al Khoury, Johny

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Restoration of endothelin-1-induced impairment in endothelium-dependent relaxation by interleukin-10 in murine aortic rings
pp. 557-565(9)
Authors: Zemse, Saiprasad M.; Hilgers, Rob H.P.; Simkins, G. B.; Rudic, R. Daniel; Webb, R. Clinton

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Urinary protein profiling with surface-enhanced laser desorption/ionization time-of-flight mass spectrometry in ETB receptor-deficient rats
pp. 566-570(5)
Authors: Raila, Jens; Kalk, Philipp; Pfab, Thiemo; Thöne-Reineke, Christa; Godes, Michael; Yanagisawa, Masashi; Schweigert, Florian J.; Hocher, Berthold

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Effect of the putative novel selective ETA-receptor antagonist HJP272, a 1,3,6-trisubstituted-2-carboxy-quinol-4-one, on infection-mediated premature delivery
pp. 571-575(5)
Authors: Olgun, Nicole; Patel, Hardik J.; Stephani, Ralph; Wang, Wei; Yen, Haoting; Reznik, Sandra E.

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