Target-finding time for microtubules interacting with catastrophe-suppressing drugs

Author: Feizabadi, M S.

Source: Canadian Journal of Physics, Volume 86, Number 5, May 2008 , pp. 763-766(4)

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Abstract:

The target-finding time for microtubules interacting with catastrophe-suppressing drugs is investigated in this study. In the steady state of microtubules interacting with catastrophe-suppressing drugs, two types of microtubules exist, those with and those without drug tips. This work shows that microtubules in the first group are slower in finding a target than those in the second group. This result is consistent with experimental findings.PACS Nos.: 87.16.Ka, 87.16.Ac, 87.10.+e, 87.15.Rn

Nous étudions le temps de localisation de cible pour des microtubules interagissant avec des médicaments suppresseurs de catastrophe. Dans le régime stationnaire de microtubules interagissant avec des médicaments suppresseurs, existent deux types de microtubules, un avec un bout médicamenté l'autre non. Nous trouvons que les microtubules du premier groupe localisent la cible moins rapidement que ceux du second groupe, un résultat en accord avec les résultats expérimentaux.[Traduit par la Rédaction]

Document Type: Research article

Publication date: 2008-05-01

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