Transcriptional regulation of ompF2, an ompF paralogue, in Yersinia pestis
Abstract:A regulatory circuit composed of three porins (OmpF, OmpC, and OmpX) and two transcriptional regulators (OmpR and CRP) has previously been characterized in Yersinia pestis. In this follow-up study, OmpF2, an OmpF paralogue, was integrated into this regulatory circuit. Only basal expression was detected for ompF2 in the wild-type strain under different osmotic conditions. The ompF2 transcription was dramatically enhanced with increasing medium osmolarity in the ompR null mutant background. The CRP regulator had no regulatory effect on ompF2 under the growth conditions tested.
Document Type: Research Article
Affiliations: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People’s Republic of China.
Publication date: 2011-07-01
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- Published since 1954, this monthly journal contains new research in the field of microbiology including applied microbiology and biotechnology; microbial structure and function; fungi and other eucaryotic protists; infection and immunity; microbial ecology; physiology, metabolism and enzymology; and virology, genetics, and molecular biology. It also publishes review articles and notes on an occasional basis, contributed by recognized scientists worldwide.
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