Skip to main content

Streptococcus salivarius mutants defective in mannose phosphotransferase systems show reduced sensitivity to mutacins I-T9 and R-3B

Buy Article:

$50.00 plus tax (Refund Policy)


Twenty-four mutacin-producing Streptococcus mutans strains were screened for their propensity to produce class II one-peptide bacteriocin using a deferred antagonism assay. Streptococcus salivarius and 3 mutants defective in their mannose phosphotransferase systems (mannose-PTS) were used as sensitive strains to identify which mannose-PTS could act as the docking site for class II one-peptide bacteriocin activity. We observed that only 2 strains of S. mutans, T9 and 3B, potentially produce class II one-peptide bacteriocin, namely mutacins I-T9 and R-3B, but with no preference for any mannose-PTS complex as a target.

La capacité de produire des bactériocines monopeptidiques de classe II a été examinée chez 24 souches de Streptococcus mutans productrices de mutacines par un test d’antagonisme différé. Streptococcus salivarius et 3 mutants défectueux dans leurs systèmes de transport du mannose par phosphotransférase ont été utilisés comme souches sensibles dans le but d’identifier lequel des sytèmes de transport du mannose pouvait agir comme site d’intéraction pour l’activité des bactériocines monopeptidiques de classe II. Nous avons observé que seulement 2 souches de S. mutans, T9 et 3B, produisent potentiellement des bactériocines monopeptidiques de classe II, à savoir les mutacines I-T9 et R-3B, mais sans aucune préférence pour aucun des complexes de transport du mannose pour cible.

Document Type: Research Article

Publication date: 2010-08-01

More about this publication?
  • Published since 1954, this monthly journal contains new research in the field of microbiology including applied microbiology and biotechnology; microbial structure and function; fungi and other eucaryotic protists; infection and immunity; microbial ecology; physiology, metabolism and enzymology; and virology, genetics, and molecular biology. It also publishes review articles and notes on an occasional basis, contributed by recognized scientists worldwide.
  • Information for Authors
  • Submit a Paper
  • Subscribe to this Title
  • Terms & Conditions
  • Sample Issue
  • Reprints & Permissions
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free ContentFree content
  • Partial Free ContentPartial Free content
  • New ContentNew content
  • Open Access ContentOpen access content
  • Partial Open Access ContentPartial Open access content
  • Subscribed ContentSubscribed content
  • Partial Subscribed ContentPartial Subscribed content
  • Free Trial ContentFree trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more