Authors: Mohammadizadeh, Mohammad R.; Azizian, Javad; Teimouri, Fatemeh; Mohammadi, Ali A.; Karimi, Ali R.; Tamari, Esmail

Source: Canadian Journal of Chemistry, Volume 86, Number 9, September 2008 , pp. 925-929(5)

Publisher: NRC Research Press

Abstract:

A versatile and highly efficient procedure has been introduced for preparation of spiro pyridodipyrimidines during the investigation of the reaction of 1,3-dimethyl-6- aminouracil with isatin derivatives, ninhydrin, and acenaphthoquinone under classical or microwave-assisted solvent-free conditions.Key words: isatin, ninhydrin, acenaphtoquinone, 1,3-dimethyl-6-aminouracil, solvent-free.

Dans le cadre d'une étude de la réaction du 1,3-diméthyl-6-aminouracil avec des dérivés de l'isatine, la ninhydrine et l'acénaphtoquinone dans des conditions classiques ou des conditions sans solvant, assistées par des microondes, on a développé une méthode versatile et très efficace de préparation de spiropyridodipyrimidines.Mots-clés : isatine, ninhydrine, acénaphtoquinone, 1,3-diméthyl-6-amino-uracile, sans solvant.[Traduit par la Rédaction]

Document Type: Research article

Publication date: 2008-09-01

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