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Time course alterations of plasma obestatin and growth hormone levels in response to short-term anaerobic exercise training in college women

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Obestatin is a 23-amino-acid peptide encoded by the same gene as ghrelin. Because there is a paucity of data concerning the effects of exercise on obestatin, this study investigated the effect of anaerobic exercise training-detraining on obestatin and growth hormone (GH) plasma levels. Ten young female volunteers participated. Blood was collected 24 h before, and 24 h, 48 h and 7 days after the training. The data indicate that anaerobic training caused a significant reduction in GH levels but had no effect on plasma obestatin concentrations.

L’obestatine est un peptide constitué de 23 acides aminés encodé par le même gène que la grhéline. Il y a peu d’études sur les effets de l’exercice physique sur l’obestatine; cette étude se propose donc d’analyser les effets de l’entraînement et de l’arrêt de l’entraînement en condition anaérobie sur les concentrations plasmatiques d’obestatine et de l’hormone de croissance (GH). Dix jeunes femmes se portent volontaires pour cette étude. On prélève des échantillons de sang 24 h avant le début de l’entraînement, puis 24 h, 48 h et 7 jours après l’arrêt de l’entraînement. Les variations des concentrations d’obestatine ne sont pas significatives; par contre, les concentrations de GH diminuent significativement. D’après ces observations, l’entraînement anaérobie suscite une diminution significative de la concentration de GH, mais n’a aucun effet sur les concentrations plasmatiques d’obestatine.

Document Type: Research Article

Publication date: December 1, 2008

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  • This bimonthly journal has a 30-year history of publishing, first as the Canadian Journal of Sport Sciences, and later as the Canadian Journal of Applied Physiology. It publishes original research articles, reviews, and commentaries, focussing on the application of physiology, nutrition, and metabolism to the study of human health, physical activity, and fitness. The published research, reviews, and symposia will be of interest to exercise physiologists, physical fitness and exercise rehabilitation specialists, public health and health care professionals, as well as basic and applied physiologists, nutritionists, and biochemists.
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