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HLA alleles and haplotypes in the Turkish population: relatedness to Kurds, Armenians and other Mediterraneans

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Abstract:

Turkish and Kurdish HLA profiles are studied for the first time. The comparative study of their allele frequencies, characteristic haplotypes, genetic distances with other Mediterraneans is complemented by neighbor-joining dendrograms and correspondence analyses. Turks, Kurds, Armenians, Iranians, Jews, Lebanese and other (Eastern and Western) Mediterranean groups seem to share a common ancestry: the older “Mediterranean” substratum. No sign of the postulated Indo-European (Aryan) invasion (1200 B.C.) is detected by our genetic analysis. It is concluded that this invasion, if occurred, had a relatively few invaders in comparison to the already settled populations, i.e. Anatolian Hittite and Hurrian groups (older than 2000 B.C.). These may have given rise to present-day Kurdish, Armenian and Turkish populations.
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Keywords: Algerians; Armenians; Berbers; Cretans; Egyptians; Greeks; HLA; Iberians; Iranians; Jews; Kurds; Lebanese; Turks

Document Type: Research Article

Affiliations: 1: Department of Immunology and Molecular Biology, H. 12 de Octubre, Universidad Complutense, Madrid, Spain 2: Dept. Medical Biology, University of Istanbul. Istanbul, Turkey 3: Institute for Clinical and Experimental Medicine, Prague, Czechoslovakia

Publication date: 2001-04-01

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