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Formerly Pharmacology & Toxicology

Publisher: Wiley-Blackwell

Volume 96, Number 3, March 2005

Molecular Modelling of Drug Targets: The Past, the Present and the Future
pp. 151-155(5)
Authors: Dahl, Svein G.; Sylte, Ingebrigt

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Prediction of Drug Metabolism and Interactions on the Basis of in vitro Investigations
pp. 167-175(9)
Authors: Pelkonen, Olavi; Turpeinen, Miia; Uusitalo, Jouko; Rautio, Arja; Raunio, Hannu

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The Use of in vitro Data in Risk Assessment
pp. 176-181(6)
Authors: Bernauer, Ulrike; Oberemm, Axel; Madle, Stephan; Gundert-Remy, Ursula

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Application of Full Physiological Models for Pharmaceutical Drug Candidate Selection and Extrapolation of Pharmacokinetics to Man
pp. 193-199(7)
Authors: Parrott, Neil; Jones, Hannah; Paquereau, Nicolas; Lavé, Thierry

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Modeling and Monte Carlo Simulations in Oral Drug Absorption
pp. 200-205(6)
Authors: Dokoumetzidis, Aristides; Kosmidis, Kosmas; Argyrakis, Panos; Macheras, Panos

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Pharmacokinetic/Pharmacodynamic Modelling in Oncological Drug Development
pp. 206-211(6)
Authors: Karlsson, Mats O.; Anehall, Therese; Friberg, Lena E.; Henningsson, Anja; Kloft, Charlotte; Sandström, Marie; Xie, Rujia

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Mechanism-Based Modeling of Complex Biomedical Systems
pp. 212-224(13)
Authors: Mosekilde, Erik; Sosnovtseva, Olga V.; Holstein-Rathlou, Niels-Henrik

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Model Systems Based on Experimental Animals for Studies on Drug Metabolism in Man: (Mini)Pig Cytochromes P450 3A29 and 2E1
pp. 244-245(2)
Authors: Anzenbacherová, Eva; Baranová, Jana; Zuber, Roman; Pěchová, Alena; Anzenbacher, Pavel; Souček, Pavel; Martínková, Jiřina

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Pupil Reaction: A Valid Sensitive Clinical Biomarker for 5-HT1A Compounds
pp. 246-246(1)
Authors: Boettcher, Michael; Heinig, Roland; Wensing, Georg; Kuhlmann, Jochen

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Low-Dose Methotrexate Pharmacokinetics and Pharmacodynamics in the Therapy of Severe Psoriasis
pp. 247-248(2)
Authors: Chladek, Jaroslav; Grim, Jiri; Martinkova, Jirina; Simkova, Marie; Vaneckova, Jaroslava

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Expression of MRP2 and MDR1 and Other Hepatic Markers in Hepatocytes in situ and WRL 68 Cells in vitro
pp. 249-250(2)
Authors: Cizkova, Dana; Mokry, Jaroslav; Micuda, Stanislav; Osterreicher, Jan; Martinkova, Jirina

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Predictive Model for Identifying Potential CYP2D6 Inhibitors
pp. 251-253(3)
Authors: Crivori, Patrizia; Poggesi, Italo

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Evaluation of a Physiologically-Based Pharmacokinetic Approach for Simulating the First-Time-In-Animal Study
pp. 254-256(3)
Authors: Germani, Massimiliano; Crivori, Patrizia; Rocchetti, Maurizio; Burton, Philip S.; Wilson, Alan G. E.; Smith, Mark E.; Poggesi, Italo

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The Effect of Mdr1 Induction on the Pharmacokinetics of Rhodamine 123 in Rats
pp. 257-258(2)
Authors: Micuda, Stanislav; Mundlova, Lucie; Mokry, Jaroslav; Osterreicher, Jan; Cermanova, Jolana; Cizkova, Dana; Martinkova, Jirina

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Dissolution – Bioequivalence Non-Correlations
pp. 262-264(3)
Authors: Mircioiu, Constantin; Mircioiu, Ion; Voicu, Victor; Miron, Dalia

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A Pharmacokinetic-Pharmacodynamic Model for Predicting Tumour Growth Inhibition in Mice: A Useful Tool in Oncology Drug Development
pp. 265-268(4)
Authors: Rocchetti, Maurizio; Poggesi, Italo; Germani, Massimiliano; Fiorentini, Francesco; Pellizzoni, Cinzia; Zugnoni, Paola; Pesenti, Enrico; Simeoni, Monica; De Nicolao, Giuseppe

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Optimizing Drug Regimens in Cancer Chemotherapy
pp. 269-270(2)
Author: Iliadis, Athanassios

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