@article {Pedersen:1 March 2000:0901-9928:110,
	author = "Pedersen K.L.",
	author = "Pedersen S.N.",
	author = "Christiansen L.B.",
	author = "Korsgaard B.",
	author = "Bjerregaard P.",
	title = "The Preservatives Ethyl-, Propyl- and Butylparaben are Oestrogenic in an in vivo Fish Assay",
	journal = "Pharmacology & Toxicology",
	volume = "86",
	year = "1 March 2000",
	abstract = ": <P></P> The widely used phenolic preservatives ethylparaben, propylparaben, butylparaben and their common metabolite <I>p</I>-hydroxybenzoic acid were tested for their ability to evoke an oestrogenic response <I>in vivo</I>. Yolk protein induction in sexually immature rainbow trout was used as an oestrogen-specific endpoint after repeated injections of the compounds. All tested parabens were oestrogenic in doses between 100 and 300 mg/kg, while the metabolite showed no activity. Ethylparaben was found to be approximately sixty times weaker than propyl- and butylparaben which had oestrogenic potencies comparable to those previously found for bisphenol A.<P></P>",
	pages = "110-113(4)",
	url = "http://www.ingentaconnect.com/content/mksg/pto/2000/00000086/00000003/art00003"
}