Skip to main content

Dramatic response of chronic ulcerating necrobiosis lipoidica to ultraviolet A1 phototherapy

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

We report on a 52-year-old female patient with chronic, ulcerating necrobiosis lipoidica (NL) who dramatically responded to ultraviolet A1 (UVA1) phototherapy. The patient had NL on her right shin for more than 30 years without evidence of diabetes mellitus. Treatment with a variety of local and systemic agents failed to prevent progression into ulceration, which necessitated repeated surgical interventions in the past. When the patient presented again with torpid ulcers at the periphery of previously grafted skin, high-dose UVA1 phototherapy was initiated. Improvement occurred rapidly and after 22 irradiations and a total exposure dose of 1480 J/cm2, the ulcers had healed completely. During a follow-up period of 6 years, two minor recurrences were successfully retreated with UVA1 phototherapy.

Keywords: UVA1 phototherapy; ulcerating necrobiosis lipoidica

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1600-0781.2010.00543.x

Affiliations: 1: Department of General Dermatology, Medical University of Vienna, Vienna, Austria 2: Seibersdorf Labor GmbH, Seibersdorf, Austria

Publication date: December 1, 2010

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Partial Open Access Content
Partial Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more