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Unsuccessful treatment of recalcitrant cutaneous discoid lupus erythematosus with photodynamic therapy

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Abstract:

Discoid lupus erythematosus (DLE) can be a therapeutic challenge. Antimalarials and topic steroids are the first-line standard therapies, while systemic steroids, immunomodulators (as azathioprine, methotrexate, cyclosporine), retinoids (acitretin), thalidomide, auranofin and dapsone are used as second-line therapies. We report two patients with recalcitrant DLE who were treated with three and two sessions of 5-aminolevulinic photodynamic therapy without an improvement and with a bad tolerance to the therapy.

Keywords: Discoid lupus erythematosus; photodynamic therapy

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1600-0781.2010.00506.x

Affiliations: Department of Dermatology, Hospital de Fuenlabrada, Madrid, Spain

Publication date: 2010-06-01

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