Unsuccessful treatment of recalcitrant cutaneous discoid lupus erythematosus with photodynamic therapy
Authors: Romero-Maté, Alberto; Castaño-Suárez, Esther; García-Donoso, Carmen; Martínez-Morán, Cristina; Meseguer-Yebra, Carmen; Borbujo, Jesús
Source: Photodermatology Photoimmunology & Photomedicine, Volume 26, Number 3, June 2010 , pp. 156-158(3)
Abstract:Discoid lupus erythematosus (DLE) can be a therapeutic challenge. Antimalarials and topic steroids are the first-line standard therapies, while systemic steroids, immunomodulators (as azathioprine, methotrexate, cyclosporine), retinoids (acitretin), thalidomide, auranofin and dapsone are used as second-line therapies. We report two patients with recalcitrant DLE who were treated with three and two sessions of 5-aminolevulinic photodynamic therapy without an improvement and with a bad tolerance to the therapy.
Document Type: Research Article
Affiliations: Department of Dermatology, Hospital de Fuenlabrada, Madrid, Spain
Publication date: June 1, 2010