Warty and clear-cell Bowen's disease successfully treated with photodynamic treatment

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Abstract:

Clear cell Bowen's disease (BD) is a rare histopathological subtype of BD, characterized by epidermal atypical keratinocytes with clear-cell changes exceeding 80% of the tumor population. Warty and clear cell Bowen's disease (WCCBD) is a recently described variant of clear cell BD, with verrucous and hyperkeratotic surface changes in addition to pathological features consisting of an extremely acanthotic epidermis, hyperkeratosis and clear-cell changes. Herein we present a 72-year-old man with a 1-year history of tumoral lesion located on the left cheek with a diagnosis of WCCBD, in whom we achieved excellent result with photodynamic treatment. To the best of our knowledge, this is the second reported case of this entity.

Keywords: Bowen's disease; clear-cell changes; photodynamic treatment

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1600-0781.2009.00482.x

Affiliations: Department of Dermatology, Gaziosmanpasa University School of Medicine, Tokat, Turkey

Publication date: February 1, 2010

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