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Photodynamic therapy for the treatment of actinic cheilitis

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Abstract:

Although actinic cheilitis is a common disease, it should be treated carefully because it can undergo malignant transformation. We report a case of actinic cheilitis treated with photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA), with satisfactory outcome in both clinical and pathological aspects. Actinic cheilitis is a pathologic condition affecting mainly the lower lip caused by long-term exposure of the lips to the UV radiation in sunlight. Analogous to actinic keratosis of the skin, actinic cheilitis is considered as a precancerous lesion and it may develop into squamous cell carcinoma. We report a case of actinic cheilitis treated with PDT using ALA, with satisfactory outcome in both clinical and pathological aspects.

Keywords: 5-aminolevulinic acid; actinic cheilitis; photodynamic therapy

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1600-0781.2007.00299.x

Affiliations: Department of Dermatology, Aichi Medical University, Aichi, Japan

Publication date: 2007-10-01

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