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Narrow-band ultraviolet B treatment for vitiligo, pruritus, and inflammatory dermatoses

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Abstract:

Background:

Narrow-band ultraviolet B (NB-UVB) therapy has been used successfully for the treatment of inflammatory and pigmentary skin disorders including atopic dermatitis, psoriasis, mycosis fungoides, polymorphous light eruption, and vitiligo. Methods:

This is a retrospective review of the treatment outcomes of 117 consecutive patients with vitiligo, pruritus, and other inflammatory dermatoses, excluding those with psoriasis and CTCL, who were treated with NB-UVB between 1998 and 2001 at our institution. Results:

Approximately 80% of all patients showed improvement in their condition. NB-UVB phototherapy was well tolerated, with no serious adverse effects. In patients with vitiligo, 6.4% had an abnormal thyroid-stimulating hormone level and 6.5% had anemia. Conclusion:

NB-UVB may be considered as a viable therapeutic option in the treatment of vitiligo, pruritus, and other inflammatory dermatoses. Long-term adverse effects and cost–benefit analysis of NB-UVB therapy compared to other treatment modalities remain to be determined.

Keywords: phototherapy; pruritus; ultraviolet; vitiligo

Document Type: Research Article

DOI: https://doi.org/10.1034/j.1600-0781.2003.00039.x

Publication date: 2003-08-01

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