Skip to main content

Correlation between bathing time and photosensitivity in 8-methoxypsoralen (8-MOP) bath PUVA

Buy Article:

The full text article is temporarily unavailable.

We apologise for the inconvenience. Please try again later.


Bath PUVA (psoralen plus ultraviolet A) using 8-methoxypsoralen has become increasingly popular in recent years as an effective treatment option for a continuously expanding range of skin disorders. Among the various variables of bath PUVA treatment, the impact of bathing time on photosensitivity has never been investigated in detail. We therefore determined the threshold UVA dose for erythema induction after different bathing periods. A marked influence of bathing time on photosensitivity was found. Increasing the soaking period from 5 min to 30 min resulted in a greater than 60% reduction of the minimal phototoxic and minimal perceptible phototoxic dose. Our results demonstrate that the duration of the psoralen bath is a critical parameter in bath PUVA treatment and has a major influence on UVA dose requirements.

Keywords: bath PUVA; photosensitivity; soaking time

Document Type: Short Communication

Affiliations: Division of Special and Environmental Dermatology, Department of Dermatology, University of Vienna Medical School, Department of Dermatology, Donauspital/SMZ-Ost, Vienna, Austria

Publication date: August 1, 2000


Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more