Skip to main content

The neuro-immuno-cutaneous system and ultraviolet radiation

Buy Article:

The full text article is temporarily unavailable.

We apologise for the inconvenience. Please try again later.

Numerous cells are closely associated with cutaneous nerve fibers, which through the action of neuropeptides are able to modulate cellular function. Anatomical and physicological links between immune cells and nerves and other cells in skin are so close that we propose the concept of a neuro-immuno-cutaneous system (NICS). Under the impact of ultraviolet radiation (UVR) virtually all properties of the NICS are modified. UVR induces melanin synthesis and immunosuppression, events in which neuropeptides, especially melanocyte stimulating hormone (MSH) and the calcitonin gene-related peptide CGRP, play a role.

No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Langerhans cell; nerve fiber; neuropeptide; skin; ultraviolet radiation

Document Type: Short Communication

Affiliations: Department of Dermatology, University Hospital, Saint-Etienne, France

Publication date: 2000-04-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more