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Factors influencing the photo‐reproduction of hydroa vacciniforme lesions

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Hydroa vacciniforme vesicles can be reproduced experimentaly with repetitive UVA irradiations, but this photo‐reproduction is not constant. The aim of this study was to search for the factors that influence photo‐reproduction. To reproduce hydroa vacciniforme lesions six patients underwent repetitive UVA and polychromatic irradiations on the back. In four patients out of six, UVA irradiation with high doses induced papulo‐vesicular lesions. Photo‐induced lesions were very close to those induced by sunlight. Photo‐reproduction failed when phototesting was done after or shortly before remission. Therefore, the absence of photo‐reproduction appears to be a good prognostic factor.
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Document Type: Original Article

Affiliations: Department of Dermatology of Caen, France

Publication date: 01 June 1997

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