Skip to main content

Enigmas of Pterorhodin, a Red Melanosomal Pigment of Tree Frogs

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Melanosomes observed in dermal melanophores of adult leaf frogs contain a unique wine red pigment identified as pterorhodin, a pteridine dimer never before found in any vertebrate. This type of melanosome, almost twice as large as the typical eumelanin melanosome, contains a small electron dense core of eumelanin surrounded by a concentric fibrous mass of pterorhodin. Dermal melanophores of larval leaf frogs contain small eumelanin melanosomes that transform at metamorphosis through the gradual accumulation of pterorhodin on the eumelanin surface to form the compound melanosomes of adults. This process may be mediated by thyroxine. No explanation for the unique presence of pterorhodin in leaf frogs has yet surfaced. A variety of tree frog species from Australia and Papua New Guinea also possess pterorhodin and the large melanosome suggesting that tree frogs from the New World and those from Australia are closely related and may have been separated during continental drift. Several of the unsolved problems posed by the emergence of pterorhodin in a unique melanosome are discussed.

Keywords: Hormones; Melanosomes; Phylogeny; Pteridines; Pterorhodin

Document Type: Research Article

DOI: http://dx.doi.org/10.1034/j.1600-0749.2003.00075.x

Affiliations: Department of Cell Biology & Anatomy, University of Arizona, Tucson, AZ, USA

Publication date: October 1, 2003

mksg/pcr/2003/00000016/00000005/art00014
dcterms_title,dcterms_description,pub_keyword
6
5
20
40
5

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more