Immunological Reviews

A golden era of opportunity in immunotherapy discovery and development
pp. 5-6(2)
Author: Chan, Andrew C.

Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics
pp. 7-19(13)
Authors: Feldmann, Marc; Maini, Sir Ravinder N.

IL-1, IL-18, and IL-33 families of cytokines
pp. 20-38(19)
Authors: Arend, William P.; Palmer, Gaby; Gabay, Cem

How the study of children with rheumatic diseases identified interferon-α and interleukin-1 as novel therapeutic targets
pp. 39-59(21)
Authors: Pascual, Virginia; Allantaz, Florence; Patel, Pinakeen; Palucka, A. Karolina; Chaussabel, Damien; Banchereau, Jacques

The role of IL-21 in regulating B-cell function in health and disease
pp. 60-86(27)
Authors: Ettinger, Rachel; Kuchen, Stefan; Lipsky, Peter E.

Th17 cells in human disease
pp. 87-113(27)
Authors: Tesmer, Laura A.; Lundy, Steven K.; Sarkar, Sujata; Fox, David A.

Strategies for use of IL-10 or its antagonists in human disease
pp. 114-131(18)
Authors: O'Garra, Anne; Barrat, Franck J.; Castro, Antonio G.; Vicari, Alain; Hawrylowicz, Catherine

Therapeutic targeting of Janus kinases
pp. 132-142(11)
Authors: Pesu, Marko; Laurence, Arian; Kishore, Nandini; Zwillich, Samuel H.; Chan, Gary; O'Shea, John J.

CTLA-4: a key regulatory point in the control of autoimmune disease
pp. 143-155(13)
Authors: Scalapino, Kenneth J.; Daikh, David I.

BAFF blockade for systemic lupus erythematosus: will the promise be fulfilled?
pp. 156-174(19)
Authors: Ramanujam, Meera; Davidson, Anne

Understanding the mechanistic basis in rheumatoid arthritis for clinical response to anti-CD20 therapy: the B-cell roadblock hypothesis
pp. 175-185(11)
Authors: Silverman, Gregg J.; Boyle, David L.

Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways
pp. 186-201(16)
Author: Ware, Carl F.

Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease
pp. 202-220(19)
Author: Browning, Jeffrey L.

Modulating tone: the overture of S1P receptor immunotherapeutics
pp. 221-235(15)
Authors: Rosen, Hugh; Gonzalez-Cabrera, Pedro; Marsolais, David; Cahalan, Stuart; Don, Anthony S.; Sanna, M. Germana

Integrin-associated proteins as potential therapeutic targets
pp. 236-251(16)
Authors: Cantor, Joseph M.; Ginsberg, Mark H.; Rose, David M.

The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis
pp. 252-270(19)
Authors: Noss, Erika H.; Brenner, Michael B.

Development of TLR inhibitors for the treatment of autoimmune diseases
pp. 271-283(13)
Authors: Barrat, Franck J.; Coffman, Robert L.

B-lymphocyte contributions to human autoimmune disease
pp. 284-299(16)
Authors: Yanaba, Koichi; Bouaziz, Jean-David; Matsushita, Takashi; Magro, Cynthia M.; St.Clair, E. William; Tedder, Thomas F.

The spectrum of complement alternative pathway-mediated diseases
pp. 300-316(17)
Author: Holers, V. Michael

Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections
pp. 317-333(17)
Authors: Ha, Sang-Jun; West, Erin E.; Araki, Koichi; Smith, Kendall A.; Ahmed, Rafi

Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism
pp. 334-360(27)
Authors: Gibbons, Carrie; Sykes, Megan

Reprogramming the immune system: co-receptor blockade as a paradigm for harnessing tolerance mechanisms
pp. 361-370(10)
Authors: Waldmann, Herman; Adams, Elizabeth; Cobbold, Stephen

Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
pp. 371-390(20)
Authors: Brusko, Todd M.; Putnam, Amy L.; Bluestone, Jeffrey A.

CD4⁺ T-regulatory cells: toward therapy for human diseases
pp. 391-421(31)
Authors: Allan, Sarah E.; Broady, Raewyn; Gregori, Silvia; Himmel, Megan E.; Locke, Natasha; Roncarolo, Maria Grazia; Bacchetta, Rosa; Levings, Megan K.