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A golden era of opportunity in immunotherapy discovery and development
Chan, Andrew C.
Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics
Feldmann, Marc; Maini, Sir Ravinder N.
IL-1, IL-18, and IL-33 families of cytokines
Arend, William P.; Palmer, Gaby; Gabay, Cem
How the study of children with rheumatic diseases identified interferon-α and interleukin-1 as novel therapeutic targets
Pascual, Virginia; Allantaz, Florence; Patel, Pinakeen; Palucka, A. Karolina; Chaussabel, Damien; Banchereau, Jacques
The role of IL-21 in regulating B-cell function in health and disease
Ettinger, Rachel; Kuchen, Stefan; Lipsky, Peter E.
Th17 cells in human disease
Tesmer, Laura A.; Lundy, Steven K.; Sarkar, Sujata; Fox, David A.
Strategies for use of IL-10 or its antagonists in human disease
O'Garra, Anne; Barrat, Franck J.; Castro, Antonio G.; Vicari, Alain; Hawrylowicz, Catherine
Therapeutic targeting of Janus kinases
Pesu, Marko; Laurence, Arian; Kishore, Nandini; Zwillich, Samuel H.; Chan, Gary; O'Shea, John J.
CTLA-4: a key regulatory point in the control of autoimmune disease
Scalapino, Kenneth J.; Daikh, David I.
BAFF blockade for systemic lupus erythematosus: will the promise be fulfilled?
Ramanujam, Meera; Davidson, Anne
Understanding the mechanistic basis in rheumatoid arthritis for clinical response to anti-CD20 therapy: the B-cell roadblock hypothesis
Silverman, Gregg J.; Boyle, David L.
Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways
Ware, Carl F.
Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease
Browning, Jeffrey L.
Modulating tone: the overture of S1P receptor immunotherapeutics
Rosen, Hugh; Gonzalez-Cabrera, Pedro; Marsolais, David; Cahalan, Stuart; Don, Anthony S.; Sanna, M. Germana
Integrin-associated proteins as potential therapeutic targets
Cantor, Joseph M.; Ginsberg, Mark H.; Rose, David M.
The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis
Noss, Erika H.; Brenner, Michael B.
Development of TLR inhibitors for the treatment of autoimmune diseases
Barrat, Franck J.; Coffman, Robert L.
B-lymphocyte contributions to human autoimmune disease
Yanaba, Koichi; Bouaziz, Jean-David; Matsushita, Takashi; Magro, Cynthia M.; St.Clair, E. William; Tedder, Thomas F.
The spectrum of complement alternative pathway-mediated diseases
Holers, V. Michael
Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections
Ha, Sang-Jun; West, Erin E.; Araki, Koichi; Smith, Kendall A.; Ahmed, Rafi
Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism
Gibbons, Carrie; Sykes, Megan
Reprogramming the immune system: co-receptor blockade as a paradigm for harnessing tolerance mechanisms
Waldmann, Herman; Adams, Elizabeth; Cobbold, Stephen
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
Brusko, Todd M.; Putnam, Amy L.; Bluestone, Jeffrey A.
CD4+ T-regulatory cells: toward therapy for human diseases
Allan, Sarah E.; Broady, Raewyn; Gregori, Silvia; Himmel, Megan E.; Locke, Natasha; Roncarolo, Maria Grazia; Bacchetta, Rosa; Levings, Megan K.
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