Authors: Pera, Pilar Isla¹; Vasallo, Joaquin Moncho²; Rabasa, Alberto Torras; Salinas, Federico Oppenheimer³; Pérez, Laureano Fernández Cruz; Brulles, María José Ricart³

Source: Clinical Transplantation, Volume 23, Number 5, September/October 2009 , pp. 600-605(6)

Publisher: Wiley-Blackwell

Abstract:

Isla P, Moncho J, Torras A, Oppenheimer F, Fernández-Cruz L, Ricart MJ. Quality of life in simultaneous pancreas-kidney transplant recipients.

Clin Transplant 2009: 23: 600-605. © 2009 John Wiley & Sons A/S. Abstract:  Background: 

Simultaneous pancreas-kidney transplantation (SPK Tx) allows dialysis and insulin therapy to be discontinued and improves the complications of diabetes mellitus type 1 (DM1). This study measure quality of life (QoL) in SPK transplant recipients and determine if there are differences in QoL between these patients and those with DM1 in renal replacement therapy (RRT). Methods: 

Short Form Health Survey 36-Item (SF-36) was administered to 69 SPK transplant recipients and 34 patients with DM1 under RRT. A descriptive analysis, multiple linear regression, ANOVA, and ordinal regression (PLUM) models were constructed. Results: 

QoL was higher in SPK transplant recipients than in patients receiving RRT. The best results were in the recently transplanted patients. Respect to Spanish population the men with SPK transplants scored higher on vitality and lower on general health, role limitations-physical and role limitations-emotional. Women with SPK transplants scored lower on general health. Among patients under RRT, men scored lower on the general health, physical functioning, vitality, and bodily pain while women scored lower on all dimensions. In both groups, greater age was associated with better mental health. Conclusion: 

Positive predictive factors of QoL are SPK Tx and age while negative predictive factors are female sex and RRT.

Keywords: chronic renal failure; diabetes mellitus; quality of life; renal replacement therapy; simultaneous pancreas-kidney transplantation

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1399-0012.2009.01054.x

Affiliations: 1: Public Health Department, Nursing School, Universitat de Barcelona, Barcelona 2: Public Health Department, Nursing School, Universidad Alicante, Alicante 3: Institut Clínic de Nefrología i Urología. Hosp. Clínic de Barcelona, Barcelona

Publication date: 2009-09-01

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