Patch testing with thin-layer chromatograms of chamomile tea in patients allergic to sesquiterpene lactones

Authors: Lundh, Kerstin; Gruvberger, Birgitta; Möller, Halvor; Persson, Lena; Hindsén, Monica; Zimerson, Erik; Svensson, Åke; Bruze, Magnus

Source: Contact Dermatitis, Volume 57, Number 4, October 2007 , pp. 218-223(6)

Publisher: Wiley-Blackwell

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Abstract:

Patients with contact allergy to sesquiterpene lactones (SLs) are usually hypersensitive to Asteraceae plant products such as herbal teas. The objective of this study was to show sensitizers in chamomile tea by patch testing with thin-layer chromatograms. Tea made from German chamomile was separated by thin-layer chromatography. Strips of the thin-layer chromatograms were used for patch testing SL-positive patients. 15 (43%) of 35 patients tested positively to 1 or more spots on the thin-layer chromatogram, with many individual reaction patterns. Patch testing with thin-layer chromatograms of German chamomile tea showed the presence of several allergens.

Keywords: chamomile; contact allergy; parthenolide; sesquiterpene lactones; thin-layer chromatography; tea

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1600-0536.2007.01226.x

Affiliations: 1: Department of Occupational and Environmental Dermatology, Malmö University Hospital, Lund University, Malmö

Publication date: 2007-10-01