Sensitization to propolis in 1255 children undergoing patch testing

Authors: Francesca Giusti; Roberta Miglietta; Patrizia Pepe; Stefania Seidenari

Source: Contact Dermatitis, Volume 51, Numbers 5-6, November 2004 , pp. 255-258(4)

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Abstract:

To investigate the frequency and the features of contact sensitization to propolis in children, we patch tested 1255 consecutive children suspected of allergic contact dermatitis with propolis 20% petrolatum over an 8-year period (1995–2002). Positive responses were observed in 5.9% of patch-tested subjects, with a significantly higher frequency in boys than in girls. The dermatitis was localized mainly on the face, hands and limbs. A significant linear increase in the annual frequency of propolis allergy was noted. Confirming literature data, a significant association with balsam of Peru sensitivity was present in children reacting to propolis, linked to the presence of common constituents in the 2 substances. In conclusion, based on our data, we suggest that propolis should not be used in topical products for children because of its high sensitization rate at the paediatric age.

Keywords: allergic contact dermatitis; children; patch tests; propolis

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.0105-1873.2004.00455.x

Affiliations: 1: Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy

Publication date: 2004-11-01