A bioactive bone cement containing Bis-GMA resin and A–W glass-ceramic as an augmentation graft material on mandibular bone

Authors: Fujimura K.1; Bessho K.2; Okubo Y.2; Segami N.1; Iizuka T.2

Source: Clinical Oral Implants Research, Volume 14, Number 5, October 2003 , pp. 659-667(9)

Publisher: Wiley-Blackwell

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Abstract:

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The potential of a bioactive bone cement (BABC) as an onlay graft material for the mandible with and without the periosteum was investigated in rabbits. Its matrix consists of bisphenol-alpha-glycidyl methacrylate (Bis-GMA) and triethylene-glycol dimetacrylate (TEGDMA) and its filler is silane-treated CaO–SiO2–P2O5–MgO–CaF2 glass (A–W glass-ceramic) powder. The BABC was pasted onto the mandible under the periosteum in Group 1, and onto the mandible with the periosteum removed in Group 2 and allowed to set in situ. In both groups, the cement–bone interface was filled by new bone at 4, 12 and 48 weeks, and bone grew from adjacent bone tissue into the cement–soft tissue interface at 12 and 48 weeks. There were no differences in the rate of bone formation between the groups. The shearing strength increased progressively from 0.25±0.10 MPa (mean±SD) at week 1 to 7.98±0.62 MPa at week 48. The results suggest that the BABC has good handling properties, a high bonding strength and good biocompatibility, and that it has potential for clinical application as a substitute material for autogenous bone transplantation.

To cite this article:

Fujimura K, Bessho K, Okubo Y, Segami N, Iizuka T. A bioactive bone cement containing Bis-GMA resin and A–W glass-ceramic as an augmentation graft material on mandibular bone.

Clin. Oral Impl. Res. 14, 2003; 659–667

Keywords: A–W-glass-ceramic; bioactive bone cement; bis-GMA resin; osteoconduction

Document Type: Research article

DOI: http://dx.doi.org/10.1034/j.1600-0501.2003.00975.x

Affiliations: 1: Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Ishikawa, Japan 2: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Publication date: 2003-10-01

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