Bipolar affective disorder in a male with a deletion of Y chromosome a case report
Authors: Olajossy, Marcin1; Olajossy-Hilkesberger, Luiza1; Tkaczuk-W
ach, Joanna2
Source: Bipolar Disorders, Volume 7, Number 3, June 2005 , pp. 298-301(4)
Publisher: Blackwell Publishing
Abstract:
Olajossy M, Olajossy-Hilkesberger L, Tkaczuk-W
ach J. Bipolar affective disorder in a male with a deletion of Y chromosome a case report. Bipolar Disord 2005: 7: 298301. © Blackwell Munksgaard, 2005 We report on a 25-year-old male with bipolar disorder, dysmorphic features and a deletion of the long arm of Y chromosome. A potential association between sex chromosome abnormalities and a susceptibility to major psychiatric disorders has been documented. However there have been very few reports on the coincidence of Y chromosome aberrations with bipolar disorder. Cytogenetic studies have contributed to the identification of several disease genes. Karyotyping of patients with bipolar disorder in order to identify candidate regions for linkage studies has been recommended.
Keywords: bipolar disorder; chromosomal abnormality; chromosome Y; deletion
Document Type: Research article
DOI: 10.1111/j.1399-5618.2005.00198.x
Affiliations: 1: Psychiatry 2: Reproduction and Andrology, University Medical School, Lublin, Poland

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