Evaluation of rapid diagnostic tests for malaria in Swedish travellers

$48.00 plus tax (Refund Policy)

Download / Buy Article:

Abstract:

Bronner U, Karlsson L, Evengård B. Evaluation of rapid diagnostic tests for malaria in Swedish travellers. APMIS 2010; 119: 88–92.

Rapid diagnostic tests (RDTs) for malaria have become valuable tools for the diagnosis of malaria in both endemic and non-endemic areas. During a 7-year period, first the MalaQuick rapid test and then the NOW Malaria test, were evaluated by well-trained laboratory technicians in a university hospital laboratory of parasitology. A total of 635 blood samples were selected from 4731 blood specimens obtained from travellers at the emergency department, at wards and at out-patient clinics. The samples were analysed by microscopy and RDT. Malaria parasites were detected in the blood films of 134 (21%) samples. The sensitivity of the RDT for Plasmodium falciparum was 97.7% (84 of 86 samples) with a negative predictive value of 99.6%. The two false-negative results were associated with low levels of parasitaemia. For non-falciparum species the sensitivity was only 58.3% (28 of 48 samples). Based on the excellent ability of the RDTs to detect P. falciparum infections, we recommend the use of the NOW Malaria test as a complement to microscopy in the laboratory.

Keywords: Rapid testing; evaluation; malaria; travellers

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1600-0463.2010.02696.x

Affiliations: 1: Infectious Diseases Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm 2: Laboratory of Parasitology, Department of Clinical Microbiology, Karolinska University Hospital Solna, Stockholm 3: Division of Infectious Diseases, Department of Clinical Microbiology, Umeå University, Umeå, Sweden

Publication date: February 1, 2011

Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more