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Four cases of distinctive meningiomas with Zellballen growth pattern

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Dong Y, Zhou X, Wu B, Wang J, Ma H, Zhou H, Jiang S, Lu G, Hu Q. Four cases of distinctive meningiomas with Zellballen growth pattern. APMIS 2009; 117: 936–40.

Meningiomas are attributed to those tumours with slow-growing pattern occurring predominantly in middle-aged or elderly patients. Fifteen histological variants have been described based on the variable histomorphological features. Herein we report four cases with specific Zellballen growth pattern, giving the tumours a ‘paraganglioma-like’ general aspect. The diagnosis of meningiomas was confirmed by immunohistochemical and ultrastructural findings. Histopathologists should be aware of this specific morphology which can lead to misdiagnosis.

Keywords: Meningioma; Zellballen growth pattern; paraganglioma

Document Type: Research Article


Affiliations: 1: Department of Pathology, Clinical School of Medical College of Nanjing University/Nanjing Jinling Hospital, Nanjing 2: The Center for Molecular Imaging Research, Department of Radiology, Nanjing Jinling Hospital, Nanjing, China

Publication date: December 1, 2009


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