Antibiotic prophylaxis in cardiac surgery—general principles


Source: Apmis, Volume 115, Number 9, September 2007 , pp. 1012-1015(4)

Publisher: Wiley-Blackwell

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Källman J, Friberg Ö. Antibiotic prophylaxis in cardiac surgery—general principles. APMIS 2007;115:1012–5.

Appropriate antibiotic prophylaxis in cardiac surgery can substantially reduce the number of postoperative infections. To avoid misuse, special concerns^^such as timing and duration of antibiotics^^must be taken into account. Increasing evidence supports that 24 h antibiotic prophylaxis is sufficient for most major surgical procedures. The prophylactic antibiotic should cover the spectrum of bacteria that are likely to be encountered. The emergence of MRSA raises special questions of antibiotic choice as well as route of administration.

Keywords: Antibiotic prophylaxis; cardiac surgery

Document Type: Research Article


Affiliations: 1: Cardiothoracic Surgery and Anesthesiology, Örebro University Hospital, Örebro, Sweden 2: Departments of Infections Diseases and

Publication date: September 1, 2007

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