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Antibiotic susceptibility of blood culture isolates of anaerobic bacteria at a Norwegian university hospital

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Abstract:

Kommedal Ø, Nystad TW, Bølstad B, Digranes A. Antibiotic susceptibility of blood culture isolates of anaerobic bacteria at a Norwegian university hospital. APMIS 2007;115:956–61.

In the present study the susceptibility of 200 blood culture isolates of anaerobic bacteria to benzylpenicillin, clindamycin, metronidazole, imipenem and piperacillin-tazobactam was examined. Metronidazole, imipenem, and piperacillin-tazobactam showed the highest activity, with 98.5% of the isolates being fully susceptible to either agent. A high rate of reduced susceptibility to clindamycin among both Bacteroides spp. (37%) and Clostridium spp. (28%) was found. Almost all Bacteroides isolates were resistant to penicillin, and only 60% of Prevotella spp. were susceptible to this agent. The antibiotic susceptibility of anaerobic bacteria in Norway should be surveyed regularly.

Keywords: Anaerobic bacteria; E-test; antibiotic susceptibility; blood culture isolates

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1600-0463.2007.apm_537.x

Affiliations: Department of Microbiology and Immunology, The Gade Institute, Haukeland University Hospital, Bergen, Norway

Publication date: August 1, 2007

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