Skip to main content

How to outwit the enemy: dendritic cells face Salmonella: Review article

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Biedzka-Sarek M, Skurnik M. How to outwit the enemy: dendritic cells face Salmonella. APMIS 2006;114:589–600.

Salmonella enterica serovar Typhi causes typhoid fever, a serious life-threatening systemic infection. In mice, a similar disease is caused by Salmonella enterica serovar Typhimurium. During typhoid fever, soon after attachment to the mucosal surface of the gut, bacteria come into contact with the dendritic cells (DCs). The ability to sample antigens, process and present them to naıÐve and mature T cells, in the context of major histocompatibility complex molecules, makes DCs indispensable for mounting a specific and efficient immune response to invading pathogens. These bacteria, however, have evolved a number of mechanisms to interfere with or subvert DC functions. This review aims to describe how Salmonella clashes with dendritic cells at different stages of infection as well as the war strategies of these two opposing sides.

Keywords: Salmonella; antigen presentation; dendritic cells; review

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1600-0463.2006.apm_465.x

Publication date: 2006-09-01

  • Access Key
  • Free ContentFree content
  • Partial Free ContentPartial Free content
  • New ContentNew content
  • Open Access ContentOpen access content
  • Partial Open Access ContentPartial Open access content
  • Subscribed ContentSubscribed content
  • Partial Subscribed ContentPartial Subscribed content
  • Free Trial ContentFree trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more