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Nonspecific granulomatous prostatitis with calculous ductal ectasia and extensive Paneth cell-like epithelial metaplasia: Case report

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Abstract:

Dikov D, Vassilev I, Dimitrakov J. Nonspecific granulomatous prostatitis with calculous ductal ectasia and extensive Paneth cell-like epithelial metaplasia: a case report. APMIS 2005;113:564–7.

We present a case of nonspecific granulomatous prostatitis in combination with calculous ductal ectasia and extensive epithelial Paneth cell-like metaplasia in a TURP-specimen. Our report highlights the importance of calculous ductal obstruction and stasis of secretions in the etiopathogenesis of this type of prostatitis. The observed extensive Paneth cell-like metaplastic change in adjacent epithelial cells most likely represents a phenotypic adaptive mechanism directed against foreign antigens and nondegradable lipids in the stagnant intraluminal debris.

Keywords: Paneth cell-like metaplasia; Prostate; calculosis; ductal ectasia; eosinophilic metaplasia; nonspecific granulomatous prostatitis

Document Type: Case Report

DOI: http://dx.doi.org/10.1111/j.1600-0463.2005.apm_215.x

Affiliations: 1: Pathology and 2: Nephrology/Urology, Medical University, Plovdiv, Bulgaria

Publication date: August 1, 2005

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