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White variants of Trichophyton violaceum isolated in Ethiopia

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Abstract:

Woldeamanuel Y, Leekassa R, Petrini B, Chryssanthou E. White variants of Trichophyton violaceum isolated in Ethiopia. APMIS 2005;113:708–12.

Certain dermatophytes are geographically restricted and endemic in particular parts of the world, while other species may have a sporadic but worldwide distribution. Trichophyton violaceum is one of the most common dermatophytes causing tinea capitis, and is the predominant cause of tinea in Africa, South America and the Indian subcontinent. Among 1187 dermatophyte isolates collected from Ethiopian patients with various types of tinea, 32 isolates had uncharacteristic phenotypic features. Based on conventional methods complemented by sequence analysis of the rDNA ITS2 region, these isolates were identified as white variants of T. violaceum. This is the first time that white isolates of T. violaceum have been identified in Ethiopia.

Keywords: DNA sequencing; Dermatophytes; internal transcribed spacer region

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1600-0463.2005.apm_311.x

Affiliations: 1: Department of Microbiology, Immunology and Parasitology, Faculty of Medicine, Addis Ababa University, 2: All African Leprosy Rehabilitation and Training Center, Addis Ababa, Ethiopia, and 3: Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden

Publication date: October 1, 2005

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