Skip to main content

Usefulness and limitations of ultrasound-guided core biopsy in the diagnosis of musculoskeletal tumours

Buy Article:

$43.00 plus tax (Refund Policy)

López JI, del Cura JL, Zabala R, Bilbao FJ. Usefulness and limitations of ultrasound-guided core biopsy in the diagnosis of musculoskeletal tumours. APMIS 2005;113:353–60.

Ultrasound-guided needle biopsy is a safe and efficient diagnostic method increasingly used in the initial approach to superficial and deep musculoskeletal tumours. However, so far no general consensus has been reached regarding its reliability. During a 6-year period (1999–2004), biopsies were taken from 188 patients (100 females, 88 males; age average 55.8 years) with musculoskeletal tumours under ultrasound guidance using 18G BioPince® or 14G ProMag® 2.2 true-cut type needles. Cytological (imprints and cytocentrifugates) and histological material was obtained for diagnosis in every case. The lower extremity (59 cases) and the abdominal wall (29 cases) were the most commonly affected sites. Benign/reactive tumours (77 cases), metastatic epithelial malignancies (40 cases), and sarcomas (36 cases) were most frequently diagnosed. In 180 (95.75%) cases, core needle results were concordant with the definitive diagnosis (97 true positives and 83 true negatives). Relevant diagnostic discordance was seen in 8 (4.25%) cases (8 false negatives and 0 false positives). Sensitivity, specificity and positive and negative predictive values were 92%, 100%, 100%, and 91%, respectively. Ultrasound-guided core biopsy is thus a useful method in the initial approach to musculoskeletal tumours that allows correct patient management in the vast majority of cases.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Soft tissue tumour; bone tumour; core biopsy; diagnosis; ultrasound

Document Type: Research Article

Affiliations: 1: Radiology, Hospital de Basurto, The Basque Country University, Bilbao, Spain 2: Anatomic Pathology and

Publication date: 2005-05-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more