Skip to main content

Molecular genetic methods in diagnosis and direct characterization of acute bacterial central nervous system infections

Buy Article:

$43.00 plus tax (Refund Policy)

Taha MK, Olcén P. Molecular genetic methods in diagnosis and direct characterization of acute bacterial central nervous system infections. APMIS 2004;112:753–70.

Acute bacterial infection of the central nervous system requires rapid and adequate management. Etiological diagnosis is hence crucial. Moreover, the epidemic threat of certain bacteria necessitates a reliable characterization of the involved bacterial strains to follow the spread of epidemic strains. Conventional identification and characterization of etiological agents are basically based on culture and identification of bacterial markers most frequently by serological assays. Molecular identification and characterization of bacteria have been employed. They provide more reliable analysis of bacterial isolates. Molecular methods for non-culture diagnosis of bacterial infections have recently been developed. In many cases, the molecular assays have decreased the identification time of positive cultures and rescued detection of pathogens in culture-negative clinical samples.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Acute bacterial infection; PCR; bacteria; epidemiological marker; meningitis; molecular diagnosis

Document Type: Research Article

Affiliations: National Reference Laboratory for Pathogenic Neisseria, Department of Clinical Microbiology,University Hospital, Örebro, Sweden

Publication date: 2004-12-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more