Skip to main content

Two cases of nondura-based clear cell meningioma of the cauda equina: Case report

Buy Article:

$51.00 plus tax (Refund Policy)


Payano M, Kondo Y, Kashima K, Daa T, Yatsuka T, Kida H, Nakayama I, Yokoyama I. Two cases of nondura-based clear cell meningioma of the cauda equina. APMIS 2004;112:141–7.

Clear cell meningioma is a rare disorder. We report two cases of nondura-based clear cell meningioma of the cauda equina, one in a 24-year-old male and the other in a 19-year-old female. Both patients had complained of numbness and spontaneous pain in the lower back and limbs for several months. Magnetic resonance imaging and computed tomography scanning revealed an intradural tumor in the cauda equina in each case. At surgery, a neurilemoma was suspected, because each of the tumors had displaced nerve roots and had attached to one of the nerve roots without any adherence to the dura. Light microscopy revealed that both tumors were well-demarcated with a thin capsule and consisted mainly of clear, glycogen-rich, polygonal cells with vague whorl formations, and of copious deposits of hyalinized blocky collagen in the stroma and perivascular areas. The neoplastic cells were immunopositive for vimentin and epithelial membrane antigen, but immunonegative for S-100 protein and chromogranin A. Positive nuclei for MIB-1 were very few in both cases, and PCNA-labeling indices were 12.1% and 24.7%, respectively. No local recurrence has been seen for 61 months and for 52 months, respectively.

Keywords: Cauda equina; blocky collagen; clear cell meningioma; prognosis

Document Type: Research Article


Affiliations: 1: Pathology and 2: Orthopedics, Oita University Faculty of Medicine, Oita, and 3: Oita Orthopedic Hospital, Oita, Japan

Publication date: February 1, 2004


Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more