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Adenoma of the esophagus with intracytoplasmic mucoid bodies: Case report

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Abstract:

Lindboe CF, Matre J, Nesland JM. Adenoma of the esophagus with intracytoplasmic mucoid bodies. APMIS 2004;112:29–33.

We report a tubular adenoma of the esophagus in a 79–year-old man. The tumour had progressed to an intramucosal carcinoma at follow-up 6 months later. The adenoma displayed a peculiar and heterogeneous histological picture with non-dysplastic and cystic areas alternating with those of a typical tubular adenoma. The tumour revealed a strong and diffuse expression of cytokeratin 7 and basal cell cytokeratin, whereas cytokeratin 20 was focally positive only. The most remarkable finding, however, was the demonstration of intracytoplasmic inclusion-like mucoid bodies of the epithelial cells in a small area of the adenomatous component. These inclusions stained PAS positive and alcian blue negative, and electron microscopy revealed a homogeneous structure without viral-like particles.

Keywords: Esophagus; adenoma; immunohistochemistry; inclusions; mucoid bodies

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1600-0463.2004.apm1120105.x

Affiliations: 1: Department of Internal Medicine, Sørlandet Sykehus HF, Kristiansand, and 2: Department of Pathology, The Norwegian Radium Hospital, University of Oslo, Oslo, Norway

Publication date: 2004-01-01

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