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Sequence analysis of the hemagglutinin gene of measles virus isolates in Denmark 1997–1998: no evidence of persistent circulation of measles virus in Denmark

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The hemagglutinin-coding region of 17 virus samples from 12 measles cases in Denmark during 1997–1998 was analysed by partial nucleotide sequencing. The cases appeared as three sporadic cases and two epidemics, both with a limited time course and geographical distribution. The measles strains identified from the three sporadic cases and two epidemics could be allocated to five different previously well-defined sequence groups consistent with the assumption that cases of measles in Denmark are due to repeated introduction from abroad rather than persistent circulation of strains in the population.

Keywords: Measles virus; molecular epidemiology, hemagglutinin gene

Document Type: Original Article


Affiliations: 1: Department of Clinical Microbiology, Rigshospitalet, Copenhagen, 2: Department of Virology, and 3: Department of Epidemiology, Statens Serum Institut, Denmark

Publication date: April 1, 2000

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