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The significance of second lumbrical-interosseous latency comparison in the diagnosis of carpal tunnel syndrome

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Argyriou AA, Karanasios P, Makridou A, Makris N. The significance of second lumbrical-interosseous latency comparison in the diagnosis of carpal tunnel syndrome.

Acta Neurol Scand 2009: 120: 198–203.

© 2008 The Authors Journal compilation © 2008 Blackwell Munksgaard. Aim – 

To assess the significance of the second lumbrical-interosseous latency (2LI-DML) comparison in the diagnosis of carpal tunnel syndrome (CTS). Patients and methods – 

We examined 150 consecutive hands of patients referred with suspected CTS, using the 2LI-DML test and other standard measures of median nerve function. Correlations of the 2LI-DML test with standard tests were computed. Results – 

Hundred and four hands were electrophysiologically confirmed to have CTS. The 2LI-DML test was abnormal in 99/104 (95.2%) hands with CTS with a mean value of 1.54 ± 1.12 ms. Among the other measures, the orthodromic median–ulnar palmar velocity comparison was the most frequently abnormal test (95/104 hands, 91.3%), followed by the double-peak morphology of orthodromic sensory action potential from digit 4 (94/104, 90.4%). The 2LI-DML test significantly correlated, either positively or negatively, with all other standard tests. Conclusion – 

The 2LI-DML comparison is highly sensitive in diagnosing CTS, even in mild cases in which standard tests fail to detect abnormalities.
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Keywords: carpal tunnel syndrome; diagnosis; neurophysiology; second lumbrical-interosseous latency test

Document Type: Research Article

Publication date: 2009-09-01

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