@article {Waje-Andreassen:2007:0001-6314:150, author = "Waje-Andreassen, U. and Naess, H. and Thomassen, L. and Eide, G. E. and Vedeler, C. A.", title = "Long-term mortality among young ischemic stroke patients in western Norway", journal = "Acta Neurologica Scandinavica", volume = "116", number = "3", year = "2007", abstract = "Waje-Andreassen U, Naess H, Thomassen L, Eide GE, Vedeler CA. Long-term mortality among young ischemic stroke patients in western Norway.
Acta Neurol Scand: 116: 150-156.©2007 The Authors Journal compilation © 2007 Blackwell Munksgaard. Objectives - To obtain data on long-term mortality among young ischemic stroke patients compared with controls in this population-based study. Material and methods - We used Kaplan-Meier survival analysis to compare 232 patients aged 15-49 years with first-ever cerebral infarction in 1988-1997 and 453 controls followed from inclusion to death or 1 August 2005 for 2515 and 5558 person-years respectively. In a subanalysis of 192 patients, we compared risk factor variables using the Kaplan-Meier method and log-rank testing. We applied a Cox proportional hazards model to adjust for multiple risk factors. Results - Forty-five patients and nine controls died during follow-up (P < 0.0005). Independent risk factors for mortality were active tumor disease (P < 0.0005), high consumption of alcohol (P < 0.0005), coronary atherosclerosis (P < 0.001), living alone (P < 0.02), seizures (P < 0.04) and smoking (P = 0.08). Conclusions - Long-term mortality was significantly increased among young stroke patients, mainly due to such lifestyle factors as high consumption of alcohol and tobacco.", pages = "150-156", url = "http://www.ingentaconnect.com/content/mksg/ane/2007/00000116/00000003/art00003", doi = "doi:10.1111/j.1600-0404.2007.00822.x", keyword = "ischemic stroke, mortality, young patients, alcohol, smoking" }