Body mass index in meralgia paresthetica: a case–control study

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Mondelli M, Rossi S, Romano C. Body mass index in meralgia paresthetica: a case–control study

Acta Neurol Scand: 116: 118–123. © 2007 The Authors Journal compilation © 2007 Blackwell Munksgaard. Objective – 

This case–control study explored the possibility of an association between body mass index (BMI) and meralgia paresthetica (MP). Patients and methods – 

A total of 104 MP cases (33 women and 71 men, mean age 51.7 ± 15.5 years) were matched for age and sex with 208 neurological and 208 dermatological controls. Differences between cases and controls were analyzed using the Wilcoxon and chi-squared tests. Odds ratio matched K controls (ORMK) and 95% confidence intervals (CI) were also calculated. Results – 

Mean BMIs were 28.0 ± 4.9 for cases and 26.0 ± 4.3 and 25.5 ± 3.9 for neurological and dermatological controls, respectively. There were significant differences between absolute BMI of cases and neurological (P < 0.01) as well as dermatological controls (P < 0.001), and also significant associations between BMI categories and MP (P = 0.008 vs neurological controls and P = 0.004 vs dermatological controls). There were significant ORMK for obesity (BMI ≥ 30) [ORMK vs neurological controls 2.04 (95% CI 1.13–3.67) and vs dermatological controls 2.5 (95% CI 1.4–4.5)]. Conclusion – 

High BMIs were associated with MP. Obesity doubled the risk of MP. MP may be related to increased pressure due to abdominal protrusion.

Keywords: body mass index; case–control study; lateral femoral cutaneous nerve; meralgia paresthetica

Document Type: Research Article


Affiliations: 1: EMG service ASL 7, Siena, Italy 2: Department of Physiopathology, Experimental Medicine and Public Health, Siena University, Siena, Italy 3: Department of Clinical Medicine and Immunological Sciences, Dermatology Section, Siena University, Siena, Italy

Publication date: August 1, 2007

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