IngentaConnect Health-related quality of life in narcolepsy

Authors: Ervik, S.¹; Abdelnoor, M.²; Heier, M.S.³; Ramberg, M.⁴; Strand, G.¹

Source: Acta Neurologica Scandinavica, Volume 114, Number 3, September 2006 , pp. 198-204(7)

Abstract:

Ervik S, Abdelnoor M, Strand G, Ramberg M. Health-related quality of life in narcolepsy.

Acta Neurol Scand 2006: 114: 198-204. © Blackwell Munksgaard 2006. Objectives -

To describe health-related quality of life in Norwegian patients with narcolepsy compared with data from the general population. Patients and methods -

Seventy-seven patients with narcolepsy with cataplexy were included in the final analysis. Health-related quality of life was assessed by SF-36 questionnaire. Results -

Men and women with narcolepsy had lower scores in all SF-36 domains, except vitality. Most profoundly affected were bodily pain (men: p = 0.0001, women: p = 0.0001), social function (men: p = 0.0001, women: p = 0.0001) and general health (men p = 0.04, women: p = 0.0001). Conclusions -

Narcolepsy has a clear negative effect on quality of life which is not sufficiently counteracted by medical treatment. We suggest that earlier diagnosis and treatment after onset of symptoms may be important in reducing the negative effects on quality of life. Special attention should be paid to the patients social functioning and general well-being.

Keywords: narcolepsy; quality of life

Document Type: Research article

DOI: 10.1111/j.1600-0404.2006.00594.x

Affiliations: 1: Norwegian Resource Centre for ADHD, Tourette Syndrome and Narcolepsy, Ullevål University Hospital, Oslo, Norway 2: Centre of Clinical Research, Ullevål University Hospital, Oslo, Norway 3: Department of Neurology, Ullevål University Hospital, Oslo, Norway 4: Norwegian Association for Sleep Disorders, Oslo, Norway

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