Abstract:

Arboix A, Manzano C, García-Eroles L, Massons J, Oliveres M, Parra O, Targa C. Determinants of early outcome in spontaneous lobar cerebral hemorrhage. Acta Neurol Scand 2006: 114: 187-192. © Blackwell Munksgaard 2006. Objective - 

To identify determinants of early outcome in spontaneous lobar hemorrhage. Materials and methods - 

From 2500 acute stroke patients included in a prospective hospital-based stroke registry over a 12-year period, 97 cases of lobar hematoma were selected. Determinants of in-hospital mortality were studied in multiple regression models. Results - 

Lobar hematomas accounted for 3.9% of all acute stroke patients and 35.9% of intracerebral hemorrhages. The presence of chronic obstructive pulmonary disease (COPD) was a significant predictive variable in the model based on demographic variables and vascular risk factors [odds ratio (OR): 17.18; 95% CI: 1.77-166.22] and in the model based on these variables plus clinical data (OR: 15.12; 95% CI: 1.27-179.59). Other predictive variables included altered consciousness, previous cerebral infarct and chronic liver disease. Conclusions - 

COPD appeared as the most important predictor of death during hospitalization after lobar cerebral hemorrhage, a finding not generally acknowledged earlier.

Keywords: chronic obstructive pulmonary disease; in-hospital mortality; lobar intracerebral hemorrhage; multivariate analysis; outcome

Document Type: Research article

DOI: 10.1111/j.1600-0404.2005.00533.x

Affiliations: 1: Cerebrovascular Division, Department of Neurology, Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona, Spain 2: Department of Internal Medicine, Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona, Spain 3: Clinical Information Systems, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain 4: Service of Pneumology, Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona, Spain