Skip to main content

Relation between vascular risk factors and cognition at age 75

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Fischer P, Zehetmayer S, Bauer K, Huber K, Jungwirth S, Tragl K-H. Relation between vascular risk factors and cognition at age 75.

Acta Neurol Scand 2006: 114: 84–90. © 2006 The Authors Journal compilation © 2006 Blackwell Munksgaard. Objective – 

Recent trends in dementia research emphasize that not only cerebrovascular events but also vascular risk factors induce, favour or cause cognitive impairment and Alzheimer's disease. Material and methods – 

We evaluated vascular risk factors (blood pressure, LDL cholesterol, HDL cholesterol, triglycerides, HbA1c, homocysteine, lipoprotein(a), fibrinogen, C-reactive protein and smoking habits) in a community-based cohort of 75-year-old individuals of two districts in Vienna (247 men, 359 women) and correlated these risk factors with overall cognition. Results – 

Pathological vascular risk factors were found frequently in the age cohort. However, the expected associations between the Mini-Mental State Examination and any cardiovascular risk factors were missing. Only individuals with a positive history of smoking showed lower cognitive capacities. Conclusions – 

We assume that cognitive dysfunction in old age is connected to factors other than the known classical and novel risk factors for the development of cardiovascular disease.

Keywords: cognition; dementia; smoking; vascular risk factors

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1600-0404.2006.00597.x

Affiliations: 1: Ludwig Boltzmann Society, L. Boltzmann Institute of Aging Research & Department of General Psychiatry, Medical University of Vienna, Vienna, Austria 2: Institute for Medical Statistics, Medical University of Vienna, Vienna, Austria 3: Ludwig Boltzmann Society, L. Boltzmann Institute of Molecular Genetic Laboratory, Danube Hospital, Vienna, Austria 4: Ludwig Boltzmann Society, L. Boltzmann Institute of Aging Research, Vienna, Austria

Publication date: August 1, 2006

mksg/ane/2006/00000114/00000002/art00002
dcterms_title,dcterms_description,pub_keyword
6
5
20
40
5

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more