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Myelopathy in primary Sjögren's syndrome: diagnostic and therapeutic aspects

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Abstract:

We report a patient with a myelopathy in primary Sjögren's syndrome, proven by salviary gland biopsy and specific antibodies. Under steroid medication, the patient had a remitting and relapsing clinical course. The severity of clinical symptoms correlated with a transient contrast uptake in spinal magnetic resonance imaging. Under a treatment with azathioprine and prednisone the patient has suffered no relapse within the last 20 months. Although this is only a case report, the combination of azathioprine and prednisone may be a valuable medication in chronic cases of Sjögren's syndrome with neurologic symptoms.

Keywords: Sjögren's syndrome; azathiopine; magnetic resonance imaging; myelopathy; treatment

Document Type: Research Article

DOI: https://doi.org/10.1034/j.1600-0404.2002.01167.x

Affiliations: 1: Department of Neurology, University of Tübingen Medical School, Tübingen, Germany, 2: Department of Internal Medicine, University of Tübingen Medical School, Tübingen, Germany, 3: Department of Neuroradiology, University of Tübingen Medical School, Tübingen, Germany

Publication date: 2002-06-01

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