Skip to main content

Prognostic factors in stroke rehabilitation: the possible role of pharmacological treatment

Buy Article:

The full text article is temporarily unavailable.

We apologise for the inconvenience. Please try again later.

Objectives – The aim of the present study was to determine the impact of commonly used and potentially detrimental drugs on rehabilitation results and to clarify their role as prognostic factors. Material and methods – The study included 154 patients admitted to a rehabilitation hospital for sequelae of a first stroke. Multivariate analyses were performed using effectiveness of treatment, evaluated by both the Barthel Index (BI) and the Rivermead Mobility Index (RMI) and low response on both of these indexes as dependent variables. Independent variables were medical, demographic and pharmacological factors. Results – The use of detrimental drugs was negatively associated with effectiveness on both BI and RMI. Severity of stroke (Canadian Neurological Scale score at admission) and hemineglect were the other negative prognostic factors that significantly entered the analyses. On the other hand, the presence of Broca's aphasia positively influenced the recovery, essentially due to prolonged length of stay. The presence of detrimental drugs and hemineglect were associated with a higher risk of low response on both BI and RMI. Conclusion – These findings confirm that the use of some drugs can influence rehabilitation results. Therefore, the choice of pharmacological treatment of stroke patients should be carefully evaluated by considering the potential detrimental effects of some drugs commonly used for the treatment of coincidental medical conditions.

No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: drugs; functional outcome; rehabilitation; stroke

Document Type: Original Article

Affiliations: 1: Fondazione S. Lucia-IRCCS, S. Lucia, Rome, Italy, 2: Clinica Neurologica, Università di Ancona, Ancona, Italy, 3: AFaR, Divisione di Neurologia, Ospedale Fatebenefratelli, Isola Tiberina, Rome, Italy,

Publication date: 2002-02-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more